50 Northern Ave
Boston, MA, 02210 United States
(617) 341-6100 †
#416 in FT Global 500 (June 2015)
Vertex Pharmaceuticals aims to cure patients with previously incurable diseases. The biotechnology firm uses an integrated, multidisciplinary approach -- employing biophysics, computer-based modeling, and functional genomics -- to speed up the discovery and development of new drugs. Its orphan drugs Kalydeco and Orkambi (launched in 2015) are used to treat cystic fibrosis; the firm is also seeking approval for the medications for other indications. Vertex has other drugs in development, including additional treatments for cystic fibrosis as well as cancer, pain, and the flu. The firm's first drug, the blockbuster hepatitis C treatment Incivek, was discontinued in 2014 after
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